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Analysis on the distinguishing features of traditional Chinese therapeutics and related statistical issues

Jingqing Hu, Jie Qiao, Deying Kang, Baoyan Liu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 203-207 doi: 10.1007/s11684-011-0138-6

Abstract: Traditional Chinese medicine (TCM) is one of the rarely existing ancient traditional medicines that holdThis paper introduces the following scientific features of traditional Chinese therapeutics: 1) its goal

Keywords： traditional Chinese therapeutics     feature     statistic    

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Thermal and energy analysis of a Chinese kang

Zhi ZHUANG, Yuguo LI, Xudong YANG, Bin CHEN, Jiaping LIU,

Frontiers in Energy 2010, Volume 4, Issue 1,   Pages 84-92 doi: 10.1007/s11708-010-0009-x

Abstract: About 67million Chinese kangs are still used by about 175million people in China todayThe kang utilizes biomass burning for space heating and hence reduces the use of commercial energy.In this paper, a macroscopic smoke flow and heat transfer model of an elevated kang is integrated inThe annual performance of the kang under different insulations of building envelope and climatic conditionsplate can be met by a proper construction of the kang and selection of the appropriate firing pattern

Keywords： Chinese kang     elevated kang     rural house thermal modeling     building energy efficiency     DeST    

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Applications of dynamical complexity theory in traditional Chinese medicine

Yan Ma,Shuchen Sun,Chung-Kang Peng

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 279-284 doi: 10.1007/s11684-014-0367-6

Abstract:

Traditional Chinese medicine (TCM) has been gradually accepted by the world.

Keywords： traditional Chinese medicine     Multiscale Entropy     dynamical complexity     system level     applications    

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Mutation analysis of KCNQ1, KCNH2, SCN5A, KCNE1 and KCNE2 genes in Chinese patients with long QT syndrome

DU Rong, TIAN Li, YUAN Guohui, LI Jin, REN Faxin, GUI Le, LI Wei, ZHANG Shouyan, KANG Cailian, YANG Junguo

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 312-315 doi: 10.1007/s11684-007-0060-0

Abstract: investigates the molecular pathology in four families with LQTS (including a family with JLNS) in the Chinesethe identification of polymorphisms and mutations related to LQTS and the Brugada Syndrome (BS) in Chinese

Keywords： recessive Jervell     LQTS-causing     population     autosomal dominant     syndrome    

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Deciphering the pharmacological mechanism of Guan-Jie-Kang in treating rat adjuvant-induced arthritis

Hudan Pan, Yanfang Zheng, Zhongqiu Liu, Zhongwen Yuan, Rutong Ren, Hua Zhou, Ying Xie, Liang Liu

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 564-574 doi: 10.1007/s11684-018-0676-2

Abstract: Traditional Chinese medicine (TCM) formulas have attracted increasing attention worldwide in the pastGuan-Jie-Kang (GJK), a prescription modified from “Wu Tou Decoction,” was found to significantly relieve

Keywords： rheumatoid arthritis     traditional Chinese medicine     pharmacological mechanism     metabolism     adjuvant-induced    

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Ant colony optimization in continuous problem

YU Ling, LIU Kang, LI Kaishi

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 4,   Pages 459-462 doi: 10.1007/s11465-007-0079-6

Abstract: Based on the analysis of the basic ant colony optimization and optimum problem in a continuous space, an ant colony optimization (ACO) for continuous problem is constructed and discussed. The algorithm is efficient and beneficial to the study of the ant colony optimization in a continuous space.

Keywords： beneficial     algorithm     efficient     continuous     ACO    

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Recent progress in the design and fabrication of MXene-based membranes

Kai Qu, Kang Huang, Zhi Xu

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 4,   Pages 820-836 doi: 10.1007/s11705-020-1997-7

Abstract: Two-dimensional membranes have attracted significant attention due to their superior characteristics, and their ability to boost both flux and selectivity have led to their reputation as potential next-generation separation membranes. Among them, emerging MXene-based membranes play significant roles in the competitive membrane-separation field. In this mini-review, we systematically discuss the assembly and separation mechanisms of these membranes. Moreover, we highlight strategies based on the crosslinking of MXene nanosheets and the construction of additional nanochannels that further enhance the permeabilities and anti-swelling properties of MXene-based membranes and meet the requirements of practical applications, such as gas-molecule sieving, ion sieving, and other small-molecule sieving. MXene nanosheets can also be used as additives that introduce specific functionalities into hybrid membranes. In addition, extended applications that use MXenes as scaffolds are also discussed.

Keywords： MXene     2D materials     membranes     separation    

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Steps of fronts in chemical engineering: An overview of the publications of FCSE

Xiaowen Zhu, Yaodong Huang, Jing-Kang Wang

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 4,   Pages 593-597 doi: 10.1007/s11705-018-1789-5

Abstract:
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DsbA-DsbA

Ye Liu,Wenyong Zhang,Xubin Yang,Guangbo Kang,Damei Wang,He Huang

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 4,   Pages 511-521 doi: 10.1007/s11705-015-1519-1

Abstract: A co-expressing system of DsbA-DsbA was suggested for the first time to enhance the soluble expression of human trypsin-1. As a control, leaderless DsbA chaperone was also co-expressed with human trypsin-1. Vectors pET39b-trypsin and pET28a-DsbA-DsbA -trypsin with the above two DsbA fusion tag were constructed. The strain with vector pET39b-trypsin expressed fusion protein DsbA-trypsin in form of inclusion bodies. While in BL21 (DE3) strain with vector pET28a-DsbA-DsbA -trypsin, the soluble expression of trypsin fusion protein was achieved. Under the optimized expression conditions, the soluble fraction accounted for about 49.43% of total DsbA-DsbA -trypsin proteins in crude supernatant. The purification yield was 4.15% by nickel chelating chromatography and 3.3 mg activated trypsin with a purity of 88.68% was obtained from 1 L LB broth. To detect the possible functions of DsbA series chaperons in trypsin fusion protein, we analyzed the primary three-dimensional structure of fusion proteins, mainly focusing on the compatibleness between trypsin and fusion chaperons. The results suggested that (1) besides the primary function in periplasm, leaderless DsbA or DsbA may also act as a signal sequences-like leader targeted to periplasm that partly relieved the pressure from fusion protein overexpression and inclusion body formation, and (2) as there was significant soluble expression of DsbA-DsbA -trypsin compared with DsbA-trypsin, DsbA may function as charge or hydrophobic balance in recombinant protein DsbA-DsbA -trypsin.

Keywords： DsbA     DsbA-DsbAmut     soluble expression     trypsin     chaperon    

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Statistical considerations for genomic selection

Huimin KANG, Lei ZHOU, Jianfeng LIU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 268-278 doi: 10.15302/J-FASE-2017164

Abstract: Genomic selection is becoming increasingly important in animal and plant breeding, and is attracting greater attention for human disease risk prediction. This review covers the most commonly used statistical methods and some extensions of them, i.e., ridge regression and genomic best linear unbiased prediction, Bayesian alphabet, and least absolute shrinkage and selection operator. Then it discusses the measurement of the performance of genomic selection and factors affecting the prediction of performance. Among the measurements of prediction performance, the most important and commonly used measurement is prediction accuracy. In simulation studies where true breeding values are available, accuracy of genomic estimated breeding value can be calculated directly. In real or industrial data studies, either training-testing approach or -fold cross-validation is commonly employed to validate methods. Factors influencing the accuracy of genomic selection include linkage disequilibrium between markers and quantitative trait loci, genetic architecture of the trait, and size and composition of the training population. Genomic selection has been implemented in the breeding programs of dairy cattle, beef cattle, pigs and poultry. Genomic selection in other species has also been intensively researched, and is likely to be implemented in the near future.

Keywords： genomic estimated breeding value     genomic selection     linkage disequilibrium     statistical methods    

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Contributions in renewable energy systems: A perspective from the latest publications of FCSE

Xiaowen Zhu, Di Xu, Jing-Kang Wang

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 632-635 doi: 10.1007/s11705-019-1904-2

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Theoretical and experimental analysis on super precision grinding of monocrystal silicon

GUO Xiaoguang, GUO Dongming, KANG Renke, JIN Zhuji

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 2,   Pages 137-143 doi: 10.1007/s11465-007-0023-9

Abstract: Through investigating the diamond-silicon grinding system, the grinding mechanism, including chip removal and subsurface damage, is discussed with the aid of the molecular dynamics (MD) approach and grinding experiments. Based on MD simulation, nanometric-grinding mechanism is analyzed from the viewpoint of instantaneous distribution of atoms, grinding force, and the potential energy between atoms and the profile of the groove. The simulation results show that some silicon atoms are deformed and piled up in front and on two sides of the abrasive surface because of the extrusion and cutting. When the energy in silicon lattice reaches its maximum value, the bonds of silicon atoms are broken and the material is removed. With the advancement of the abrasive, the silicon lattice under the abrasive surface is fractured, and then the amorphous layers are formed and propagated, which causes the subsurface damage. At the same time, some amorphous atoms are reconstructed and the degenerating layer of the machined surface is formed. Besides, the recovery of elatstic deformation occurs in the machined surface of the workpiece. In addition, the grinding experiment and profile detection with the aid of the measurment for 3D profiling are performed to verify the simulation results. The good agreement in the profile of the groove between the experimental value and the simulating value shows that MD simulation is very effective and reliable, and successful to fulfill the investigation on nanometric machining mechanism.

Keywords： machining mechanism     recovery     advancement     mechanism     subsurface    

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Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

Frontiers of Medicine doi: 10.1007/s11684-023-1040-8

Abstract: Traditional Chinese medicine (TCM) has played an important role in the prevention and treatment of coronavirusThe integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention

Keywords： traditional Chinese medicine     COVID-19     SARS-CoV-2     clinical evidence-based study     mechanism     integratedtraditional Chinese and Western medicine    

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Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China

Jian Wang, Wen Zou

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 123-126 doi: 10.1007/s11684-011-0124-z

Abstract: Traditional Chinese medicine (TCM) has become widely used in the treatment of acquired immune deficiency

Keywords： HIV/AIDS     traditional Chinese medicine    

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Individualized medicine, health medicine, and constitutional theory in Chinese medicine

Qi Wang

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 1-7 doi: 10.1007/s11684-012-0173-y

Abstract: Chinese and Western medical systems are dissimilar in terms of value orientations, thinking style, andThe Chinese constitutional theory developed in the 1970s expresses the principle behind Chinese healthThe Chinese constitutional theory divides the constitution of the Chinese population into nine categoriesIt promotes the study of the relationship of each constitution to diseases and Chinese medicine preparationdisease-differentiation, and syndrome-differentiation can be established for the development of individualized Chinese

Keywords： individualized medicine     health medicine     constitutional theory in Chinese medicine    

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Title Author Date Type Operation

Analysis on the distinguishing features of traditional Chinese therapeutics and related statistical issues

Jingqing Hu, Jie Qiao, Deying Kang, Baoyan Liu

Journal Article

Thermal and energy analysis of a Chinese kang

Zhi ZHUANG, Yuguo LI, Xudong YANG, Bin CHEN, Jiaping LIU,

Journal Article

Applications of dynamical complexity theory in traditional Chinese medicine

Yan Ma,Shuchen Sun,Chung-Kang Peng

Journal Article

Mutation analysis of KCNQ1, KCNH2, SCN5A, KCNE1 and KCNE2 genes in Chinese patients with long QT syndrome

DU Rong, TIAN Li, YUAN Guohui, LI Jin, REN Faxin, GUI Le, LI Wei, ZHANG Shouyan, KANG Cailian, YANG Junguo

Journal Article

Deciphering the pharmacological mechanism of Guan-Jie-Kang in treating rat adjuvant-induced arthritis

Hudan Pan, Yanfang Zheng, Zhongqiu Liu, Zhongwen Yuan, Rutong Ren, Hua Zhou, Ying Xie, Liang Liu

Journal Article

Ant colony optimization in continuous problem

YU Ling, LIU Kang, LI Kaishi

Journal Article

Recent progress in the design and fabrication of MXene-based membranes

Kai Qu, Kang Huang, Zhi Xu

Journal Article

Steps of fronts in chemical engineering: An overview of the publications of FCSE

Xiaowen Zhu, Yaodong Huang, Jing-Kang Wang

Journal Article

DsbA-DsbA

Ye Liu,Wenyong Zhang,Xubin Yang,Guangbo Kang,Damei Wang,He Huang

Journal Article

Statistical considerations for genomic selection

Huimin KANG, Lei ZHOU, Jianfeng LIU

Journal Article

Contributions in renewable energy systems: A perspective from the latest publications of FCSE

Xiaowen Zhu, Di Xu, Jing-Kang Wang

Journal Article

Theoretical and experimental analysis on super precision grinding of monocrystal silicon

GUO Xiaoguang, GUO Dongming, KANG Renke, JIN Zhuji

Journal Article

Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

Journal Article

Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China

Jian Wang, Wen Zou

Journal Article

Individualized medicine, health medicine, and constitutional theory in Chinese medicine

Qi Wang

Journal Article